Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.38 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16472108 | 0.91 | HSD17B10 (0.39) | NAMPTDDIT3ALDH1A1RORCIAPP | |
| SCHEMBL2894511 | 0.79 | CA2 (0.47) | DDIT3ALDH1A1HTR2A | |
| SCHEMBL184682 | 0.78 | LMNA (0.50) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL13341421 | 0.77 | MMP9 (0.52) | ALDH1A1MMP13MAPT | |
| SCHEMBL19454406 | 0.77 | DDB1 (0.54) | ALDH1A1HTR2ADDB1CRBNL3MBTL1 | |
| SCHEMBL6181601 | 0.76 | DDIT3 (0.37) | NAMPTDDIT3ALDH1A1HTR2AMMP13 | |
| SCHEMBL20300384 | 0.73 | CA1 (0.53) | NAMPTDDIT3HTR2AMMP13 | |
| SCHEMBL2651365 | 0.73 | MEP1B (0.44) | NAMPTDDIT3ALDH1A1HTR2AMMP13 | |
| SCHEMBL4541922 | 0.73 | ALDH1A1 (0.48) | ALDH1A1IAPPTDP1L3MBTL1 | |
| SCHEMBL185256 | 0.71 | DDIT3 (0.49) | NAMPTDDIT3ALDH1A1MMP13MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047798-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2009-04-16 | — | — | WO | disclosed |