Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29105992 | 0.82 | SPHK1 (0.49) | SPHK1NPC1RAB9ASPHK2F10 | |
| SCHEMBL27440338 | 0.82 | ALDH1A1 (0.49) | NPC1RAB9APRMT5MEN1KMT2A | |
| SCHEMBL28911545 | 0.81 | DGAT1 (0.49) | NPC1RAB9APRMT5KDM4EALDH1A1 | |
| SCHEMBL26695699 | 0.80 | LMNA (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28543989 | 0.78 | SLC6A7 (0.50) | SPHK1NPC1RAB9ASPHK2F10 | |
| SCHEMBL29998568 | 0.78 | CKS1B (0.57) | PRMT5KMT2A | |
| SCHEMBL27448755 | 0.78 | CKS1B (0.57) | PRMT5KMT2A | |
| SCHEMBL29106012 | 0.77 | KDM4E (0.43) | PRMT5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16037235 | 0.77 | PRMT5 (0.51) | PRMT5KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL1775467 | 0.74 | LMNA (0.64) | MEN1KMT2ASMN1; SMN2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023222115-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| CN-117062813-A | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |