Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metiazinic Acid SCHEMBL30190433 | 0.86 | LMNA (0.59) | MAOANOX1LMNAMAPTL3MBTL1 | |
| Metiazinic Acid SCHEMBL30697757 | 0.86 | LMNA (0.59) | MAOANOX1LMNAMAPTL3MBTL1 | |
| Metiazinic Acid SCHEMBL150554 | 0.86 | LMNA (0.59) | MAOANOX1LMNAMAPTL3MBTL1 | |
| Metiazinic Acid SCHEMBL10820947 | 0.86 | LMNA (0.59) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL2669527 | 0.83 | MAOA (0.47) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL629086 | 0.80 | MAOA (0.63) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL6850282 | 0.80 | MAPT (0.56) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL15101212 | 0.79 | MAPT (0.52) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL28555924 | 0.78 | NOX1 (0.57) | MAOANOX1LMNAMAPTL3MBTL1 | |
| SCHEMBL13295825 | 0.78 | BCHE (0.53) | MAOANOX1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089892-A1 | PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2008-07-31 | — | — | WO | disclosed |