Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101212 | 0.86 | MAPT (0.52) | MAPTLMNANOX1MAPK1TDP1 | |
| Metiazinic Acid SCHEMBL30697757 | 0.85 | LMNA (0.59) | MAPTLMNANOX1MAPK1TDP1 | |
| Metiazinic Acid SCHEMBL150554 | 0.85 | LMNA (0.59) | MAPTLMNANOX1MAPK1TDP1 | |
| Metiazinic Acid SCHEMBL30190433 | 0.85 | LMNA (0.59) | MAPTLMNANOX1MAPK1TDP1 | |
| Metiazinic Acid SCHEMBL10820947 | 0.85 | LMNA (0.59) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL2669592 | 0.80 | MAOA (0.54) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL13295825 | 0.80 | BCHE (0.53) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL11258846 | 0.78 | MAOA (0.56) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL28555924 | 0.77 | NOX1 (0.57) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL629086 | 0.77 | MAOA (0.63) | MAPTLMNANOX1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178466-A1 | Treatment of Microbial Infections | BIOCOPEA LIMITED (GB) | 2013-07-11 | — | — | US | disclosed |
| WO-2011058346-A1 | TREATMENT OF MICROBIAL INFECTIONS | BIOCOPEA LIMITED (GB) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178466-A1 | Treatment of Microbial Infections | HRH2, TLR5, IL5 | MAPT 4303/4885LMNA 3565/4885NOX1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.