Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | RORC | P51449 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942206 | 0.93 | KMT2A (0.69) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL2831462 | 0.88 | NPC1 (0.77) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL14025738 | 0.85 | NPC1 (0.73) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL17000091 | 0.85 | NPC1 (0.73) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL1933248 | 0.84 | RAB9A (0.61) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL20379448 | 0.84 | HTT (0.68) | NPC1KMT2AMEN1HTTROCK2 | |
| SCHEMBL13720058 | 0.83 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL7420189 | 0.83 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL27953145 | 0.83 | RAB9A (0.72) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL6203861 | 0.83 | SENP1 (0.64) | NPC1RAB9AKMT2AMEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574070-B | Synthesis method of substituted urea compound | 西华大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112574070-A | Synthesis method of substituted urea compound | 西华大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-103664704-B | A kind of synthetic N, the method for N '-disubstituted urea | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-103664704-A | Method for synthesizing N,N'-disubstituent urea | UNIV NANJING SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |