SCHEMBL26705155

SCHEMBL26705155

COC1CCN(CC2CN(C)C2)CC1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.37
EHMT2 Q96KQ7 1/20 0.33
CHRM5 P08912 1/20 0.33
ADRA2C P18825 1/20 0.33
GRM5 P41594 1/20 0.32
GRM7 Q14831 1/20 0.32
GRM3 Q14832 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24921697 0.96 ACHE (0.39) ACHEEHMT2CHRM5ADRA2CCHRM2
SCHEMBL22565042 0.85 NCF1 (0.42) ACHEEHMT2CHRM5ADRA2CCHRM2
SCHEMBL23205549 0.85 NCF1 (0.42) ACHEEHMT2CHRM5ADRA2CCHRM2
SCHEMBL15806908 0.84 ACHE (0.47) ACHEEHMT2CHRM5ADRA2C
SCHEMBL19070085 0.82
SCHEMBL26705160 0.79 SIGMAR1 (0.36) CHRM2CHRM1CHRM3
SCHEMBL26705159 0.79 CHRM5 (0.39) ACHECHRM5ADRA2C
SCHEMBL27097465 0.78 ACHE (0.62) ACHEEHMT2CHRM5ADRA2CCHRM2
SCHEMBL25134464 0.78 NCF1 (0.39) ACHECHRM5ADRA2C
SCHEMBL22703779 0.78 ACHE (0.61) ACHECHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG ACHE 3611/4885EHMT2 2623/4885CHRM5 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.