SCHEMBL26705159

SCHEMBL26705159

CN1CC(CN2CCN(CC3CN(C)C3)CC2)C1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.39
ADRA2C P18825 1/20 0.39
ACHE P22303 2/20 0.38
NCF1 P14598 1/20 0.33
CCR2 P41597 1/20 0.33
KCNH2 Q12809 1/20 0.33
CACNA2D1 P54289 1/20 0.32
CACNA1B Q00975 1/20 0.32
CACNB1 Q02641 1/20 0.32
CACNA1C Q13936 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22047347 0.95 ACHE (0.36) CHRM5ADRA2CACHENCF1CCR2
SCHEMBL24319652 0.91 ALDH1A1 (0.39) CHRM5ADRA2CACHECCR2KCNH2
SCHEMBL26705153 0.91 NCF1 (0.43) CHRM5ADRA2CACHENCF1CCR2
SCHEMBL12403098 0.90 CHRM5 (0.46) CHRM5ADRA2CACHENCF1CCR2
SCHEMBL12434924 0.90 CHRM5 (0.52) CHRM5ADRA2CACHENCF1CCR2
SCHEMBL25571696 0.89 NCF1 (0.46) CHRM5ADRA2CACHENCF1CCR2
SCHEMBL24745088 0.89 DRD2 (0.37) CHRM5ADRA2CACHESIGMAR1
SCHEMBL19590887 0.87 CHRM5 (0.56) CHRM5ADRA2CACHECYP1A2
SCHEMBL24480239 0.87 ACHE (0.44) CHRM5ADRA2CACHENCF1KCNH2
SCHEMBL26705143 0.87 KDM4E (0.33) CHRM5ADRA2CACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2023-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348427-A1 COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG CHRM5 2288/4885ADRA2C 134/4885ACHE 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.