Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26708814 | 0.96 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL26708921 | 0.89 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL5024742 | 0.88 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL26708829 | 0.82 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL10310510 | 0.82 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL10310513 | 0.80 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL26143789 | 0.79 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL26708919 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL26708801 | 0.78 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 | |
| SCHEMBL5024894 | 0.78 | ALDH1A1 (0.76) | L3MBTL1ALDH1A1ALOX15TSHRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | SRM, SMS, ARG2 | L3MBTL1 901/4885ALDH1A1 301/4885ALOX15 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.