Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26778927 | 0.88 | MAPT (0.44) | MAPTNPC1RAB9AMAPK1KDR | |
| SCHEMBL26778942 | 0.87 | MAPT (0.46) | BRAFMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL26778842 | 0.87 | ADORA3 (0.51) | BRAFNPC1RAB9AKDRADORA3 | |
| SCHEMBL26798432 | 0.79 | MAPT (0.51) | BRAFMAPTNPC1RAB9AKDR | |
| SCHEMBL26779026 | 0.78 | CDK1 (0.37) | BRAFNPC1RAB9AMAPK1ADORA3 | |
| SCHEMBL23240669 | 0.76 | BRD4 (0.53) | NPC1RAB9AADORA3ADORA2AADORA1 | |
| SCHEMBL26778651 | 0.73 | ADORA3 (0.49) | NPC1RAB9AKDRADORA3ADORA2A | |
| SCHEMBL9547503 | 0.70 | RAB9A (0.89) | MAPTNPC1RAB9AKDRCA2 | |
| SCHEMBL26778781 | 0.66 | KDM4E (0.47) | MAPK1ADORA2AADORA2BMEN1ALDH1A1 | |
| SCHEMBL26800707 | 0.66 | LMNA (0.38) | MAPTNPC1RAB9AMAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |