Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | CCR2 | P41597 | 1/20 | 0.63 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | MC4R | P32245 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138636 | 1.00 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL83548 | 1.00 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Benzene SCHEMBL27761330 | 1.00 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL152631 | 1.00 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL7062479 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL7573306 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL2223234 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL8145866 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10063607 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28172574 | 0.98 | SIGMAR1 (0.96) | SIGMAR1MEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116102565-A | Isolamine-containing spirochromone compound and preparation method and application thereof | 贵州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-113717201-B | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-115260046-A | Abietate compound and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | claimed |
| CN-115141208-A | Podophyllotoxin compound containing various ester group structures and preparation method and application thereof | 贵州大学 | 2022-10-04 | — | — | CN | claimed |
| CN-114920722-A | 7-hydroxy-3-acetyl coumarin oxime compound, preparation method and medical application thereof | 何黎琴 | 2022-08-19 | — | — | CN | claimed |
| CN-113717201-A | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-112707843-A | Novel paeonol oxime compound, preparation method and medical application thereof | 何黎琴 | 2021-04-27 | — | — | CN | claimed |
| CN-112624931-A | Pterostilbene amine compounds containing isopropanol aromatic ether structure and preparation method and application thereof | 贵州大学 | 2021-04-09 | — | — | CN | claimed |
| US-4409219-A | BACTERICIDES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-10-11 | — | — | US | claimed |
| US-4395413-A | NICOTINE ANTIALLERGEN, ANESTHETIC, ANALGESIC, HYPOTENSIVE, AND ANTIULCER AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-07-26 | — | — | US | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |
| EP-0022371-B1 | SUBSTITUTED PIPERAZINES AND PIPERIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER INC. (US) | 1983-01-19 | — | — | EP | claimed |
| US-4342762-A | USEFUL AS TRANQUILIZERS, ANALGESICS, ANTIEPILEPTIC AGENTS, AND AS A TREATMENT FOR PARKINSON'S DISEASE | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | claimed |
| US-4324786-A | SEDATIVES, ANALGESICS, ANTIINFLAMMATORY, ANTIPYRETIC | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-04-13 | — | — | US | claimed |
| US-4279905-A | GASTROINTESTINAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-07-21 | — | — | US | claimed |
| EP-0025109-A2 | 1-Benzoxepin-5(2H)-one derivatives and their salts, and processes for their preparation | Kali-Chemie Pharma GmbH (DE) | 1981-03-18 | — | — | EP | claimed |
| EP-0022371-A1 | Substituted piperazines and piperidines and pharmaceutical compositions containing them | PFIZER INC. (US) | 1981-01-14 | — | — | EP | claimed |
| US-4128643-A | 4-Quinazolinyl-guanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | claimed |