SCHEMBL83548

SCHEMBL83548

c1ccc(CN2CCNCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 1.00
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ALDH1A1 P00352 1/20 0.68
CYP2C9 P11712 1/20 0.68
TSHR P16473 1/20 0.68
CYP2C19 P33261 1/20 0.68
HIF1A Q16665 1/20 0.68
CXCR4 P61073 9/20 0.64
CHRM2 P08172 1/20 0.63
CHRM1 P11229 1/20 0.63
ADRA2C P18825 1/20 0.63
CCR2 P41597 1/20 0.63
CXCL12 P48061 1/20 0.63
BLM P54132 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
HRH3 Q9Y5N1 1/20 0.63
MC4R P32245 1/20 0.59
DRD4 P21917 1/20 0.57
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138636 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL276363 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
Benzene SCHEMBL27761330 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL152631 1.00 SIGMAR1 (1.00) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL7062479 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL7573306 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
Hydrochloric Acid SCHEMBL2223234 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL8145866 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
SCHEMBL10063607 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9
Ammonia Solution, Strong SCHEMBL28172574 0.98 SIGMAR1 (0.96) SIGMAR1MEN1KMT2AALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8033 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
EP-4651897-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS Syntis Bio, Inc. (US) 2025-11-26 EP claimed
US-12414936-B2 Compositions comprising a serotonergic tryptamine compound CAAMTECH, INC. (US) 2025-09-16 US claimed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP claimed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN claimed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN claimed
US-20250122154-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2025-04-17 US claimed
CN-119375485-A Method for improving protein methylation modification identification analysis 中国科学院大连化学物理研究所 2025-01-28 CN claimed
CN-119376200-A Photoresist stripping liquid capable of protecting GaAs and PI substrates and application thereof 芯越微电子材料(嘉兴)有限公司 2025-01-28 CN claimed
US-4279905-A GASTROINTESTINAL DISORDERS KALI-CHEMIE PHARMA GMBH (DE) 1981-07-21 US claimed
EP-0028083-A1 Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-05-06 EP claimed
EP-0025109-A2 1-Benzoxepin-5(2H)-one derivatives and their salts, and processes for their preparation Kali-Chemie Pharma GmbH (DE) 1981-03-18 EP claimed
EP-0022371-A1 Substituted piperazines and piperidines and pharmaceutical compositions containing them PFIZER INC. (US) 1981-01-14 EP claimed
EP-0018360-A1 CYCLIC DIAMINE N,N'-DISUBSTITUTED AND PROCESS FOR PREPARING THE SAME HOECHST AG (DE) 1980-11-12 EP claimed
WO-1979000426-A1 CYCLIC DIAMINE N,N'-DISUBSTITUTED AND PROCESS FOR PREPARING THE SAME HOECHST AG (DE) 1979-07-12 WO claimed
US-4128643-A 4-Quinazolinyl-guanidines HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-05 US claimed
US-4059584-A ANTIINFLAMMATORY PFIZER (US) 1977-11-22 US claimed
US-4021400-A SECONDARY AMINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-03 US claimed
US-4002623-A Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines PFIZER INC. (US) 1977-01-11 US claimed