Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30921003 | 0.79 | L3MBTL1 (0.51) | NAMPTL3MBTL1P2RX7KDM5ASLC6A7 | |
| SCHEMBL26790639 | 0.76 | ACHE (0.54) | NAMPTL3MBTL1KDM5AKDM4E | |
| SCHEMBL27491158 | 0.75 | L3MBTL1 (0.47) | NAMPTL3MBTL1P2RX7KDM5ASLC6A7 | |
| SCHEMBL28859625 | 0.75 | SMN1; SMN2 (0.51) | NAMPTL3MBTL1 | |
| SCHEMBL11100905 | 0.73 | MKNK1 (0.60) | SIGMAR1MKNK1MKNK2CHRNB2CHRNB4 | |
| SCHEMBL28578707 | 0.72 | SIGMAR1 (0.47) | L3MBTL1SIGMAR1MKNK1MKNK2RXFP1 | |
| SCHEMBL3431770 | 0.72 | P2RX7 (0.41) | NAMPTL3MBTL1SIGMAR1P2RX7MKNK1 | |
| SCHEMBL22904414 | 0.71 | NAMPT (0.42) | NAMPTL3MBTL1 | |
| SCHEMBL26790988 | 0.71 | KDM5A (0.50) | NAMPTL3MBTL1P2RX7KDM5A | |
| SCHEMBL2399787 | 0.70 | SIGMAR1 (0.79) | L3MBTL1SIGMAR1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85106742-A | The preparation method of pyridazinylimidazolicompounds compounds | — | 1986-12-31 | — | — | CN | disclosed |