Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343382 | 0.90 | PKM (0.61) | PKMHTTSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL5423815 | 0.86 | HTT (0.55) | PKMHTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL31687126 | 0.85 | PKM (0.64) | PKMSMN1; SMN2SIRT6LMNAMAPT | |
| SCHEMBL6340645 | 0.85 | TUBB4A (0.56) | PKMHTTSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL6352850 | 0.81 | PKM (0.49) | PKMHTTSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL6341219 | 0.77 | LMNA (0.79) | PKMHTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL6351710 | 0.77 | TUBB4A (0.52) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9257125 | 0.77 | PSEN1 (0.69) | PKMSIRT6LMNA | |
| SCHEMBL28051137 | 0.76 | HTT (0.61) | PKMHTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL2587301 | 0.76 | PKM (1.00) | PKMHTTSMN1; SMN2SIRT6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187246-A1 | Cell proliferation inhibitors | LI QUN (US) | 2005-08-25 | — | — | US | claimed |
| EP-1181269-B1 | CELL PROLIFERATION INHIBITORS | ABBOTT LAB (US) | 2004-02-25 | — | — | EP | claimed |
| US-20030096856-A1 | Cell proliferation inhibitors | ABBVIE INC. | 2003-05-22 | — | — | US | claimed |
| US-20030078439-A1 | Process for the preparation of cell proliferation inhibitors | ABBVIE INC. | 2003-04-24 | — | — | US | claimed |
| US-6521658-B1 | Cell proliferation inhibitors | ABBOTT LABORATORIES | 2003-02-18 | — | — | US | claimed |
| WO-2002024648-A2 | PROCESS FOR THE PREPARATION OF CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | claimed |
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | claimed |
| EP-4620466-A1 | TRIMETHOXYSTYRYL DERIVATIVES FOR USE IN THE TREATMENT OF PACLITAXEL-RESISTANT CANCER | Instituto de Investigación Biomédica de Salamanca De la Fundación Instituto Ciencia de la Salud De Castilla y León (ES) | 2025-09-24 | — | — | EP | disclosed |
| EP-3175870-A1 | MEDICAL DEVICE HAVING HYDRATION INHIBITOR | Abbott Laboratories (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-2301619-B1 | Multiple drug delivery from a balloon and a prosthesis | ABBOTT LAB (US) | 2017-05-10 | — | — | EP | disclosed |
| EP-1536850-B1 | MEDICAL DEVICE HAVING HYDRATION INHIBITOR | ABBOTT LAB (US) | 2016-08-10 | — | — | EP | disclosed |
| US-9296011-B2 | Prosthesis having varied concentration of beneficial agent | ABBOTT LABORATORIES (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150196692-A1 | MULTIPLE DRUG DELIVERY FROM A BALLOON AND A PROSTHESIS | ABBOTT LABORATORIES (US) | 2015-07-16 | — | — | US | disclosed |
| US-20030096856-A1 | Cell proliferation inhibitors | ABBVIE INC. | 2003-05-22 | — | — | US | disclosed |
| US-20030078439-A1 | Process for the preparation of cell proliferation inhibitors | ABBVIE INC. | 2003-04-24 | — | — | US | disclosed |
| US-6521658-B1 | Cell proliferation inhibitors | ABBOTT LABORATORIES | 2003-02-18 | — | — | US | disclosed |
| WO-2002024648-A2 | PROCESS FOR THE PREPARATION OF CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078439-A1 | Process for the preparation of cell proliferation inhibitors | MKI67, CCNI, CDKN1A | PKM 2047/4885HTT 1830/4885SMN1; SMN2 3964/4885 |
| US-20030096856-A1 | Cell proliferation inhibitors | MKI67, CCNI, CCNA1 | PKM 1894/4885HTT 4313/4885SMN1; SMN2 1869/4885 |
| US-20050187246-A1 | Cell proliferation inhibitors | MKI67, CCNI, CCNC | PKM 1733/4885HTT 4031/4885SMN1; SMN2 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.