Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803751 | 0.93 | IKBKB (0.42) | IKBKBPARP1HSD17B1MAP2K2MAP2K1 | |
| SCHEMBL21900873 | 0.88 | HSD17B1 (0.46) | HSD17B1TRPA1ALDH1A1MAPTTSHR | |
| SCHEMBL11243107 | 0.85 | ALDH1A1 (0.47) | IKBKBPARP1MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL28499997 | 0.83 | ALDH1A1 (0.48) | HSD17B1TRPA1ALDH1A1MAPTKDM4E | |
| SCHEMBL10818516 | 0.82 | IKBKB (0.45) | IKBKBPARP1MAP2K2MAP2K1TRPA1 | |
| SCHEMBL11243095 | 0.81 | ALDH1A1 (0.47) | IKBKBPARP1MAP2K2MAP2K1ALDH1A1 | |
| SCHEMBL23960204 | 0.79 | MKNK1 (0.44) | IKBKBPARP1MAP2K2MAP2K1TRPA1 | |
| SCHEMBL8830144 | 0.79 | ALDH1A1 (0.42) | HSD17B1TRPA1ALDH1A1MAPTKDM4E | |
| SCHEMBL20670595 | 0.79 | ALDH1A1 (0.54) | HSD17B1TRPA1ALDH1A1MAPTKDM4E | |
| SCHEMBL14072398 | 0.79 | TRPA1 (0.55) | IKBKBPARP1MAP2K2MAP2K1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381327-A1 | REACTIVE CONJUGATES | FCGR3B, FCGR1A, FCGR2A | IKBKB 3765/4885PARP1 232/4885HSD17B1 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.