Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.45 |
| ▸ | CA9 | Q16790 | 10/20 | 0.45 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583173 | 1.00 | LMNA (0.51) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL3639989 | 1.00 | LMNA (0.51) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL11801230 | 0.92 | LMNA (0.45) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL2583850 | 0.92 | LMNA (0.44) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL10894045 | 0.91 | LMNA (0.44) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL10887648 | 0.91 | ALDH1A1 (0.44) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL10894039 | 0.91 | LMNA (0.44) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL10887645 | 0.91 | ALDH1A1 (0.44) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL3642090 | 0.89 | ALB (0.47) | LMNAALDH1A1THRBSMN1; SMN2HIF1A | |
| SCHEMBL9856461 | 0.88 | LMNA (0.52) | LMNAALDH1A1THRBSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | LMNA 2032/4885ALDH1A1 997/4885THRB 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.