SCHEMBL26805683

SCHEMBL26805683

CCCCc1cc(CCCC)cc(Nc2ccc3ccn(Cc4cc(C)cc(C)c4)c3n2)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.35
▸ TP53 P04637 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ PTK2 Q05397 2/20 0.32
▸ TLR7 Q9NYK1 1/20 0.31
▸ STAT6 P42226 1/20 0.31
▸ CYP11B1 P15538 1/20 0.30
▸ CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26805652 0.88 TLR7 (0.41) PTK2TLR7STAT6
SCHEMBL26805638 0.85 TP53 (0.36) MAPTTP53LMNAPTK2TLR7
SCHEMBL26804233 0.80 EPHX2 (0.34) MAPTTP53LMNAPTK2STAT6
SCHEMBL24334795 0.78 KCNH2 (0.36) CYP11B1CYP11B2
SCHEMBL26805707 0.77 TP53 (0.35) MAPTTP53LMNAPTK2TLR7
SCHEMBL29564933 0.76 P2RX7 (0.37) PTK2CYP11B1CYP11B2
SCHEMBL24334963 0.76 P2RX7 (0.37) PTK2CYP11B1CYP11B2
SCHEMBL26804232 0.72 P2RX7 (0.34) PTK2CYP11B1CYP11B2
SCHEMBL24334965 0.69 CYP11B1 (0.39) MAPTTP53LMNACYP11B1CYP11B2
SCHEMBL29565367 0.68 MTNR1A (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382929-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382929-A1 OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND AZI2, AOC2, CCNI MAPT 1584/4885TP53 4103/4885LMNA 4280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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