Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296246 | 1.00 | MMP1 (0.64) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL2680872 | 1.00 | MMP1 (0.64) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL5086029 | 0.87 | ALDH1A1 (0.70) | MMP1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL7814579 | 0.84 | MMP1 (0.71) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL30764101 | 0.84 | MMP1 (0.71) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL7814581 | 0.84 | MMP1 (0.71) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL5177059 | 0.82 | MMP1 (0.65) | MMP1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL5176144 | 0.82 | MMP1 (0.65) | MMP1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL5176155 | 0.82 | MMP1 (0.65) | MMP1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL11842713 | 0.81 | MMP1 (0.66) | MMP1MMP2MMP9EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906945-B2 | Inhibitors of bacterial type III secretion system | MICROBIOTIX, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120114633-A1 | Inhibitors Of Bacterial Type III Secretion System | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114633-A1 | Inhibitors Of Bacterial Type III Secretion System | CLPP, TFPI, SI | MMP1 629/4885MMP2 247/4885MMP9 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.