Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802398 | 0.87 | KDM4E (0.39) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL20699038 | 0.84 | HPGD (0.37) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL19475186 | 0.84 | NLRP3 (0.47) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL21962078 | 0.82 | MTNR1A (0.45) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL25067020 | 0.81 | NLRP3 (0.45) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL22802351 | 0.78 | DRD2 (0.38) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL22802391 | 0.78 | RXRB (0.49) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL22802406 | 0.78 | KDM4E (0.36) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL29691325 | 0.75 | NLRP3 (0.42) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL23012413 | 0.75 | NLRP3 (0.42) | ALDH1A1HPGDHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834433-B2 | Compounds | INFLAZOME LIMITED (IE) | 2023-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834433-B2 | Compounds | NLRP3, NOD1, PYCARD | ALDH1A1 378/4885HPGD 275/4885HSD17B10 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.