Acrylic Acid

Acrylic Acid

SCHEMBL26846

C=CC(=O)O.F[SiH]1CCCCO1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27484365 0.79
SCHEMBL155957 0.78
Acrylic Acid SCHEMBL28173079 0.77 LMNA (0.39) LMNA
Acrylic Acid SCHEMBL557537 0.77 LMNA (0.39) LMNA
Acrylic Acid SCHEMBL27611586 0.77 LMNA (0.39) LMNA
Methane SCHEMBL20699739 0.76
SCHEMBL2683966 0.76
Tetrahydrofuran SCHEMBL246413 0.74 LMNA (0.56) LMNA
Tetrahydrofuran SCHEMBL2724272 0.74 LMNA (0.56) LMNA
Tetrahydrofuran SCHEMBL28665538 0.74 LMNA (0.56) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200166671-A1 LIPOIC ACID HYDROGELS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2020-05-28 US claimed
EP-3640270-A1 LIPOIC ACID HYDROGELS Universidade de Santiago de Compostela (ES) 2020-04-22 EP claimed
WO-2017160574-A1 CONTACT LENS WITH FLEXIBLE CENTER AND RIGID PERIPHERY THOMPSON VANCE M (US) 2017-09-21 WO claimed
US-20170261766-A1 CONTACT LENS WITH FLEXIBLE CENTER AND RIGID PERIPHERY THOMPSON VANCE M (US) 2017-09-14 US claimed
EP-2314640-B1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIV SANTIAGO COMPOSTELA (ES) 2015-07-01 EP claimed
US-8951548-B2 Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2015-02-10 US claimed
US-20110200661-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2011-08-18 US claimed
EP-2314640-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS Universidade De Santiago De Compostela (ES) 2011-04-27 EP claimed
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US claimed
CN-1930513-A Hybrid contact lens system and method QUARTER LAMBDA TECHNOLOGIES IN (US) 2007-03-14 CN claimed
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP claimed
US-7097301-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-08-29 US claimed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO claimed
EP-1546984-A1 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2005-06-29 EP claimed
US-20050018130-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2005-01-27 US claimed
WO-2004023374-A9 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES IN (US) 2004-04-29 WO claimed
WO-2004023374-A1 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES, INC. (US) 2004-03-18 WO claimed
US-20040046931-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-03-11 US claimed
US-5958194-A Gas permeable elastomer contact lens bonded with titanium and/or oxides thereof GLAZIER ALAN N (US) 1999-09-28 US claimed
EP-3822696-B1 METHOD FOR OBTAINING CONTACT LENSES WITH DYNAMICALLY CONTROLLED SAGITTA AND CLEARANCE BAUSCH & LOMB (US) 2024-06-26 EP disclosed
US-20230346596-A1 OPHTHALMIC DEVICE AVISI LTD. (IL) 2023-11-02 US disclosed
WO-2023073706-A1 OPHTHALMIC DEVICE AVISI LTD. (IL) 2023-05-04 WO disclosed
US-20230084398-A1 METHOD FOR OBTAINING CONTACT LENSES WITH DYNAMICALLY CONTROLLED SAGITTA AND CLEARANCE JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-03-16 US disclosed
EP-4138745-A1 OPHTHALMIC DEVICE Avisi Ltd. (IL) 2023-03-01 EP disclosed
US-11391964-B2 Method for obtaining contact lenses with dynamically controlled sagitta and clearance BAUSCH & LOMB INCORPORATED (US) 2022-07-19 US disclosed
EP-4004637-A1 THROUGH-BODY OCULAR COMMUNICATION DEVICES, NETWORKS, AND METHODS OF USE Tectus Corporation (US) 2022-06-01 EP disclosed
CN-114341205-A Silicone acrylates with perfluoropolyether groups 信越化学工业株式会社 2022-04-12 CN disclosed
US-11194176-B2 Through-body ocular communication devices, networks, and methods of use TECTUS CORPORATION (US) 2021-12-07 US disclosed
WO-2021214761-A1 OPHTHALMIC DEVICE AVISI LTD. (IL) 2021-10-28 WO disclosed
EP-3822696-A1 METHOD FOR OBTAINING CONTACT LENSES WITH DYNAMICALLY CONTROLLED SAGITTA AND CLEARANCE Bausch & Lomb Incorporated (US) 2021-05-19 EP disclosed
US-20210026158-A1 THROUGH-BODY OCULAR COMMUNICATION DEVICES, NETWORKS, AND METHODS OF USE TECTUS CORPORATION 2021-01-28 US disclosed
EP-3304179-B1 METHOD FOR OBTAINING CONTACT LENSES WITH DYNAMICALLY CONTROLLED SAGITTA AND CLEARANCE BAUSCH & LOMB (US) 2020-11-04 EP disclosed
US-20200292846-A1 Method For Obtaining Contact Lenses With Dynamically Controlled Sagitta And Clearance SALIX PHARMACEUTICALS, INC. 2020-09-17 US disclosed
US-20200192121-A1 CONTACT LENS FOR PRESBYOPIA WITH PINHOLE RING Anderledge Vision LLC 2020-06-18 US disclosed
US-20200166671-A1 LIPOIC ACID HYDROGELS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2020-05-28 US disclosed
EP-3640270-A1 LIPOIC ACID HYDROGELS Universidade de Santiago de Compostela (ES) 2020-04-22 EP disclosed
US-10598955-B2 Method for obtaining contact lenses with dynamically controlled sagitta and clearance BAUSCH & LOMB INCORPORATED (US) 2020-03-24 US disclosed
EP-3304179-A1 METHOD FOR OBTAINING CONTACT LENSES WITH DYNAMICALLY CONTROLLED SAGITTA AND CLEARANCE Bausch & Lomb Incorporated (US) 2018-04-11 EP disclosed
WO-2017160574-A1 CONTACT LENS WITH FLEXIBLE CENTER AND RIGID PERIPHERY THOMPSON VANCE M (US) 2017-09-21 WO disclosed
US-20170261766-A1 CONTACT LENS WITH FLEXIBLE CENTER AND RIGID PERIPHERY THOMPSON VANCE M (US) 2017-09-14 US disclosed
US-20160349535-A1 Method For Obtaining Contact Lenses With Dynamically Controlled Sagitta And Clearance MEDICIS PHARMACEUTICAL CORPORATION 2016-12-01 US disclosed
EP-2314640-B1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIV SANTIAGO COMPOSTELA (ES) 2015-07-01 EP disclosed
US-8951548-B2 Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2015-02-10 US disclosed
EP-2800553-A1 METHODS AND KITS FOR EXTENDING CONTACT LENS USE Insite Vision Incorporated (US) 2014-11-12 EP disclosed
US-20130177599-A1 METHODS AND KITS FOR EXTENDING CONTACT LENS USE INSITE VISION INCORPORATED 2013-07-11 US disclosed
WO-2013103830-A1 METHODS AND KITS FOR EXTENDING CONTACT LENS USE INSITE VISION INCORPORATED (US) 2013-07-11 WO disclosed
EP-1734398-B1 Contact lens having a uniform horizontal thickness profile COOPERVISION INT HOLDING CO LP (BB) 2013-03-13 EP disclosed
US-20120307200-A1 CONTACT LENSES HAVING HYBRID ORIENTATION FEATURES BAUSCH HEALTH US, LLC 2012-12-06 US disclosed
WO-2012166570-A1 CONTACT LENSES HAVING HYBRID ORIENTATION FEATURES BAUSCH & LOMB INCORPORATED (US) 2012-12-06 WO disclosed
US-20110200661-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2011-08-18 US disclosed
EP-2314640-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS Universidade De Santiago De Compostela (ES) 2011-04-27 EP disclosed
US-7628485-B2 Contact lens having a uniform horizontal thickness profile COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2009-12-08 US disclosed
US-7625084-B2 Contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2009-12-01 US disclosed
US-7618142-B2 Contact lenses COOPER VISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2009-11-17 US disclosed
US-7585074-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2009-09-08 US disclosed
US-20090009712-A1 Contact lens COOPERVISION,INC. (US) 2009-01-08 US disclosed
US-7401922-B2 Method and apparatus for reducing or eliminating the progression of myopia SYNERGEYES, INC. (US) 2008-07-22 US disclosed
US-7329001-B2 Methods for improving the hydrophilicity of contact lenses and contact lenses having the same SYNERGEYES, INC. (US) 2008-02-12 US disclosed
US-20080030676-A1 Contact lenses COOPERVISION, INC. (US) 2008-02-07 US disclosed
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US disclosed
US-20070109495-A1 CONTACT LENS HAVING A UNIFORM HORIZONTAL THICKNESS PROFILE COOPERVISION, INC. (US) 2007-05-17 US disclosed
WO-2007053297-A2 METHODS FOR IMPROVING THE HYDROPHILICITY OF CONTACT LENSES AND CONTACT LENSES HAVING THE SAME SYNERGEYES, INC. (US) 2007-05-10 WO disclosed
EP-1783535-A2 Contact lens having a uniform horizontal thickness profile Coopervision International Holding Company, LP. (BB) 2007-05-09 EP disclosed
EP-1783534-A2 Contact lens having a uniform horizontal thickness profile Coopervision International Holding Company, LP. (BB) 2007-05-09 EP disclosed
US-20070097315-A1 Methods for improving the hydrophilicity of contact lenses and contact lenses having the same SYNERGEYES, INC. 2007-05-03 US disclosed
EP-1281099-B1 CONTACT LENS HAVING A UNIFORM HORIZONTAL THICKNESS PROFILE COOPERVISION INT HOLDING CO LP (BB) 2007-03-28 EP disclosed
CN-1930513-A Hybrid contact lens system and method QUARTER LAMBDA TECHNOLOGIES IN (US) 2007-03-14 CN disclosed
US-20070019155-A1 CONTACT LENSES COOPERVISION, INC. (US) 2007-01-25 US disclosed
US-20070013869-A1 HYBRID CONTACT LENS SYSTEM AND METHOD DAHI ALI 2007-01-18 US disclosed
US-7163292-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2007-01-16 US disclosed
US-20060285072-A1 Hybrid contact lens system and method DAHI ALI 2006-12-21 US disclosed
EP-1734398-A2 Contact lens having a uniform horizontal thickness profile CooperVision Inc. (US) 2006-12-20 EP disclosed
US-7150529-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-12-19 US disclosed
US-20060256283-A1 Hybrid contact lens system and method LEGERTON JEROME 2006-11-16 US disclosed
US-20060256284-A1 Hybrid contact lens system and method DAHI ALI 2006-11-16 US disclosed
US-7134753-B2 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2006-11-14 US disclosed
US-7133174-B2 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2006-11-07 US disclosed
WO-2006113149-A2 METHOD AND APPARATUS FOR REDUCING OR ELIMINATING THE PROGRESSION OF MYOPIA SYNERGEYES, INC. (US) 2006-10-26 WO disclosed
US-20060238713-A1 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES INC. 2006-10-26 US disclosed
US-20060238712-A1 HYBRID CONTACT LENS SYSTEM AND METHOD DAHI ALI 2006-10-26 US disclosed
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP disclosed
US-20060232743-A1 Method and apparatus for reducing or eliminating the progression of myopia SYNERGEYES, INC. 2006-10-19 US disclosed
US-7104648-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-09-12 US disclosed
US-20060197909-A1 Hybrid contact lens system and method LEGERTON JEROME 2006-09-07 US disclosed
US-20060197910-A1 Hybrid contact lens system and method LEGERTON JEROME 2006-09-07 US disclosed
US-20060197908-A1 Hybrid contact lens system and method QUARTER LAMBDA TECHNOLOGIES, INC. 2006-09-07 US disclosed
US-7097301-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2006-08-29 US disclosed
US-20050280774-A1 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2005-12-22 US disclosed
US-6971746-B2 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2005-12-06 US disclosed
US-20050254005-A1 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2005-11-17 US disclosed
US-20050254004-A1 Contact lens having a uniform horizontal thickness profile COOPERVISION, INC. (US) 2005-11-17 US disclosed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO disclosed
EP-1546984-A1 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2005-06-29 EP disclosed
CN-1204240-C Conditioning solutions for hard contact lenz care ALCON LAB INC (US) 2005-06-01 CN disclosed
US-6857740-B2 Contact lens having a uniform horizontal thickness profile OCULAR SCIENCES, INC. (US) 2005-02-22 US disclosed
US-20050018130-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2005-01-27 US disclosed
US-20040212779-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-10-28 US disclosed
US-20040196429-A1 Contact lens having a uniform horizontal thickness profile OCULAR SCIENCES, INC. (US) 2004-10-07 US disclosed
EP-1203808-B1 Conditioning solutions for hard contact lens care ALCON LAB INC (US) 2004-09-29 EP disclosed
US-20040179167-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-09-16 US disclosed
WO-2004023374-A9 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES IN (US) 2004-04-29 WO disclosed
WO-2004023374-A1 HYBRID CONTACT LENS SYSTEM AND METHOD QUARTER LAMBDA TECHNOLOGIES, INC. (US) 2004-03-18 WO disclosed
US-20040046931-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2004-03-11 US disclosed
EP-1281099-A1 CONTACT LENS HAVING A UNIFORM HORIZONTAL THICKNESS PROFILE Ocular Sciences Inc. (US) 2003-02-05 EP disclosed
US-6486215-B2 GELLING SYSTEMS CONTAINING GALACTOMANNAN POLYSACCHARIDES AND BORATES FOR CONDITIONING HARD CONTACT LENSES ALCON MANUFACTURING, LTD. 2002-11-26 US disclosed
US-6467903-B1 Contact lens having a uniform horizontal thickness profile OCULAR SCIENCES, INC. 2002-10-22 US disclosed
US-20020149742-A1 Contact lens having a uniform horizontal thickness profile OCULAR SCIENCES, INC. 2002-10-17 US disclosed
EP-0970175-B1 CONDITIONING SOLUTIONS FOR HARD CONTACT LENS CARE ALCON LAB INC (US) 2002-10-02 EP disclosed
EP-1203808-A1 Conditioning solutions for hard contact lens care ALCON LABORATORIES, INC. (US) 2002-05-08 EP disclosed
US-20010046973-A1 Solutions for treating contact lenses ALCON RESEARCH, LTD. 2001-11-29 US disclosed
US-6316506-B2 COATING LENS WITH A CONDITIONING FORMULATION BY SOAKING LENS GALACTOMANNAN(S) AND BORATE COMPOUND, TO CREATE A GEL OR PARTIAL GEL; INSERTING LENS IN EYE ALCON LABORATORIES, INC. 2001-11-13 US disclosed
WO-2001075509-A1 CONTACT LENS HAVING A UNIFORM HORIZONTAL THICKNESS PROFILE OCULAR SCIENCES, INC. (US) 2001-10-11 WO disclosed
US-20010001789-A1 Conditioning solutions for hard contact lens care ALCON RESEARCH, LTD. 2001-05-24 US disclosed
CN-1061589-C Treatment of contact lenses with supercritical fluid BAUSCH & LOMB (US) 2001-02-07 CN disclosed
EP-0970175-A1 CONDITIONING SOLUTIONS FOR HARD CONTACT LENS CARE ALCON LABORATORIES, INC. (US) 2000-01-12 EP disclosed
US-6007771-A APPLICATION OF AN ELECTROMAGNETIC FIELD ABOUT THE CONTACT LENSES WHICH ARE HELD IN A CAVITY CONTAINING A CONDUCTIVE SOLUTION AND AN ADSORBENT MEMBRANE TO CAPTURE THE CONTAMINANTS BEING REMOVED FROM THE LENSES REHMEYER THEODORE H (US) 1999-12-28 US disclosed
CN-1236385-A Hard contact lens nursing regulating liquid ALCON LAB INC (US) 1999-11-24 CN disclosed
US-5958194-A Gas permeable elastomer contact lens bonded with titanium and/or oxides thereof GLAZIER ALAN N (US) 1999-09-28 US disclosed
WO-1999006512-A1 CONDITIONING SOLUTIONS FOR HARD CONTACT LENS CARE ALCON LABORATORIES, INC. (US) 1999-02-11 WO disclosed
CN-1142209-A Method for treating contact lenses with supercritical fluids BAUSCH & LOMB (US) 1997-02-05 CN disclosed
CN-1142209-A Method for treating contact lenses with supercritical fluids BAUSCH & LOMB (US) 1997-02-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200166671-A1 LIPOIC ACID HYDROGELS CRYAA, CRYAB, CRYZ LMNA 956/4885
US-20010001789-A1 Conditioning solutions for hard contact lens care GALC, ALG1, FUT5 LMNA 2008/4885
US-20010046973-A1 Solutions for treating contact lenses GALC, FUT5, CSGALNACT1 LMNA 1617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.