Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20247998 | 0.86 | MAOA (0.46) | HTTMAOAMAOBKMT2AMEN1 | |
| SCHEMBL2228385 | 0.79 | MEN1 (0.54) | HTTMAOBKMT2AMEN1PTGDR2 | |
| SCHEMBL20861172 | 0.75 | KMT2A (0.45) | HTTMAOAMAOBKMT2AMEN1 | |
| SCHEMBL22383534 | 0.74 | ALDH1A1 (0.45) | HTTKMT2AGAATSHRL3MBTL1 | |
| SCHEMBL20248000 | 0.73 | NAAA (0.51) | HTTTSHRL3MBTL1PTGS2 | |
| SCHEMBL20133884 | 0.73 | CYP1A2 (0.35) | HTTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL22030308 | 0.72 | MAOA (0.42) | HTTMAOAMAOBKMT2AMEN1 | |
| SCHEMBL6547365 | 0.71 | TRPA1 (0.48) | HTTMAOAMAOBKMT2AMEN1 | |
| SCHEMBL20865394 | 0.71 | MAOA (0.49) | HTTMAOAMAOBGAAL3MBTL1 | |
| SCHEMBL24403082 | 0.70 | NAAA (0.42) | HTTGAATSHRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4072670-B1 | QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS | CHIESI FARM SPA (IT) | 2023-11-22 | — | — | EP | disclosed |