SCHEMBL268519

SCHEMBL268519

CCCCC=CC#CC#CCCCCCC=CC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 6/20 0.69
PTPN7 P35236 1/20 0.45
PTPN1 P18031 1/20 0.43
PPARG P37231 2/20 0.42
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3510230 1.00 HMGCR (0.69) HMGCRPTPN7PTPN1PPARGF7
SCHEMBL1020722 0.85 HMGCR (0.64) HMGCRPTPN7PPARGPPARA
Exocarpic Acid SCHEMBL5363302 0.84 HMGCR (0.89) HMGCRPTPN7PTPN1PPARGF7
SCHEMBL28854091 0.84 HMGCR (0.89) HMGCRPTPN7PTPN1PPARGF7
SCHEMBL31429837 0.84 HMGCR (0.59) HMGCRPTPN7PTPN1PPARGF7
Exocarpic Acid SCHEMBL44849 0.84 HMGCR (0.89) HMGCRPTPN7PTPN1PPARGF7
SCHEMBL29242819 0.82 HMGCR (0.62) HMGCRPTPN7
SCHEMBL29242816 0.82 HMGCR (0.62) HMGCRPTPN7
SCHEMBL28586677 0.82 HMGCR (0.62) HMGCRPTPN7
SCHEMBL29242820 0.82 HMGCR (0.62) HMGCRPTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11952581-B2 Process for the production of polyunsaturated fatty acids in transgenic organisms BASF PLANT SCIENCE GMBH (DE) 2024-04-09 US disclosed
EP-4219670-A2 Method for producing polyunsaturated fatty acids in transgenic organisms BASF Plant Science GmbH (DE) 2023-08-02 EP disclosed
US-20220162629-A1 Process for the Production of Polyunsaturated Fatty Acids in Transgenic Organisms BASF PLANT SCIENCE GMBH (DE) 2022-05-26 US disclosed
US-20220056423-A1 PROCESSES FOR PRODUCING POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS BASF PLANT SCIENCE GMBH (DE) 2022-02-24 US disclosed
US-11180769-B2 Method for the production of multiple-unsaturated fatty acids in transgenic organisms BASF PLANT SCIENCE GMBH (DE) 2021-11-23 US disclosed
US-11168308-B2 Processes for producing polyunsaturated fatty acids in transgenic organisms BASF PLANT SCIENCE GMBH (DE) 2021-11-09 US disclosed
US-11046937-B2 Methods for conversion of the substrate specificity of desaturases BASF PLANT SCIENCE COMPANY GMBH (DE) 2021-06-29 US disclosed
EP-3083949-B1 METHODS FOR CONVERSION OF THE SUBSTRATE SPECIFICITY OF DESATURASES BASF PLANT SCIENCE CO GMBH (DE) 2020-02-12 EP disclosed
US-20190323024-A1 METHOD FOR THE PRODUCTION OF MULTIPLE-UNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS BASF PLANT SCIENCE GMBH (DE) 2019-10-24 US disclosed
US-20190270972-A1 METHODS FOR CONVERSION OF THE SUBSTRATE SPECIFICITY OF DESATURASES BASF PLANT SCIENCE CO GMBH (DE) 2019-09-05 US disclosed
EP-2061879-A2 ISOLATION AND CHARACTERIZATION OF A NOVEL PYTHIUM OMEGA 3 DESATURASE WITH SPECIFICITY TO ALL OMEGA 6 FATTY ACIDS LONGER THAN 18 CARBON CHAINS BASF Plant Science GmbH (DE) 2009-05-27 EP disclosed
EP-1937805-A2 PROCESS FOR THE PRODUCTION OF ARACHIDONIC ACID AND/OR EICOSAPENTAENOIC ACID BASF Plant Science GmbH (DE) 2008-07-02 EP disclosed
US-20080155705-A1 Method For the Production of Multiple-Unsaturated Fatty Acids in Transgenic Organisms BASF PLANT SCIENCE GMBH (DE) 2008-06-26 US disclosed
US-20080076164-A1 Method for Increasing the Content of Polyunsaturated Long-Chained Fatty Acids in Transgenic Organisms BASF PLANT SCIENCE GMBH (DE) 2008-03-27 US disclosed
US-20080076166-A1 Method For Producing Polyunsaturated Fatty Acids In Transgenic Organisms BASF PLANT SCIENCE GMBH (DE) 2008-03-27 US disclosed
WO-2008022963-A2 ISOLATION AND CHARACTERIZATION OF A NOVEL PYTHIUM OMEGA 3 DESATURASE WITH SPECIFICITY TO ALL OMEGA 6 FATTY ACIDS LONGER THAN 18 CARBON CHAINS BASF PLANT SCIENCE GMBH (DE) 2008-02-28 WO disclosed
US-20070224661-A1 for production of triglycerides with an elevated content of unsaturated fatty acids in a transgenic organism , especially of omega -3-fatty acids having more than three double bonds; allow a shift from the omega -6- to the omega -3-synthetic pathway; omega -3-desaturase BASF PLANT SCIENCE (DE) 2007-09-27 US disclosed
US-20070136892-A1 Process for the production of delta5-unsaturated fatty acids in transgenic organisms BASF PLANT SCIENCE GMBH (DE) 2007-06-14 US disclosed
EP-1790731-A2 Process for the production of delta 5-unsaturated fatty acids in transgenic organisms BASF Plant Science GmbH (DE) 2007-05-30 EP disclosed
WO-2007042510-A2 PROCESS FOR THE PRODUCTION OF ARACHIDONIC ACID AND/OR EICOSAPENTAENOIC ACID BASF PLANT SCIENCE GMBH (DE) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070136892-A1 Process for the production of delta5-unsaturated fatty acids in transgenic organisms SCD5, FADS2, ELOVL5 HMGCR 452/4885PTPN7 4838/4885PTPN1 4855/4885
US-11168308-B2 Processes for producing polyunsaturated fatty acids in transgenic organisms ELOVL3, ELOVL1, ELOVL5 HMGCR 522/4885PTPN7 4002/4885PTPN1 3940/4885
US-20080155705-A1 Method For the Production of Multiple-Unsaturated Fatty Acids in Transgenic Organisms ELOVL3, FADS2, DGAT2 HMGCR 241/4885PTPN7 4698/4885PTPN1 4569/4885
US-20220056423-A1 PROCESSES FOR PRODUCING POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS ELOVL3, ELOVL1, ELOVL5 HMGCR 522/4885PTPN7 4002/4885PTPN1 3940/4885
US-20080076166-A1 Method For Producing Polyunsaturated Fatty Acids In Transgenic Organisms FADS2, ELOVL3, ELOVL6 HMGCR 84/4885PTPN7 4667/4885PTPN1 4680/4885
US-20190270972-A1 METHODS FOR CONVERSION OF THE SUBSTRATE SPECIFICITY OF DESATURASES SCD5, SCD, FADS2 HMGCR 174/4885PTPN7 4539/4885PTPN1 4720/4885
US-11046937-B2 Methods for conversion of the substrate specificity of desaturases SCD5, SCD, FADS2 HMGCR 174/4885PTPN7 4539/4885PTPN1 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.