Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683668 | 0.85 | ACHE (0.58) | ACHEAGTR1PPARGLTB4R2AGTR2 | |
| SCHEMBL29687426 | 0.82 | AGTR1 (0.68) | AGTR1PPARGLTB4R2ABCC3ABCC4 | |
| SCHEMBL14357525 | 0.80 | AGTR1 (0.50) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL1316335 | 0.80 | ACHE (1.00) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL29598156 | 0.80 | ACHE (1.00) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL8246734 | 0.77 | ACHE (0.94) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL2471984 | 0.77 | AGTR1 (0.51) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL9671888 | 0.74 | ACHE (0.75) | ACHEAGTR1LTB4R2 | |
| SCHEMBL2692039 | 0.74 | PPARG (0.53) | ACHEAGTR1PPARGAGTR2 | |
| SCHEMBL38655977 | 0.73 | ACHE (0.89) | ACHEAGTR1LTB4R2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd (IN) | 2012-05-10 | — | — | US | claimed |
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd (IN) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | PKD1, AGTR1, NPR1 | ACHE 4453/4885AGTR1 2/4885PPARG 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.