Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2685840 | 0.85 | ACHE (0.66) | ACHEAGTR1PPARGAGTR2LTB4R2 | |
| SCHEMBL6588559 | 0.77 | AGTR1 (0.55) | ACHEAGTR1PPARGAGTR2LTB4R2 | |
| SCHEMBL9671888 | 0.73 | ACHE (0.75) | ACHEAGTR1LTB4R2 | |
| SCHEMBL1316335 | 0.73 | ACHE (1.00) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL29598156 | 0.73 | ACHE (1.00) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL2692039 | 0.73 | PPARG (0.53) | ACHEAGTR1PPARGAGTR2 | |
| SCHEMBL28470460 | 0.71 | ACHE (0.56) | ACHEAGTR1PPARGAGTR2PRKAG1 | |
| SCHEMBL8246734 | 0.70 | ACHE (0.94) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL4253889 | 0.69 | HSD17B10 (0.58) | ACHEAGTR1PPARGAGTR2 | |
| SCHEMBL7657851 | 0.69 | AGTR1 (0.59) | ACHEAGTR1PPARGAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |