DDHD2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL29659427	1.00	1/20
SCHEMBL18935828	0.96	1/20
SCHEMBL18935859	0.91	1/20
SCHEMBL18935850	0.71	1/20
SCHEMBL18935829	0.68	1/20
SCHEMBL20575996	0.67	1/20
SCHEMBL18935852	0.66	1/20
SCHEMBL20575251	0.63	1/20
SCHEMBL18935851	0.63	1/20
SCHEMBL18936205	0.60	1/20
SCHEMBL18936213	0.60	1/20
SCHEMBL18936215	0.60	1/20
SCHEMBL18936417	0.58	1/20
SCHEMBL18935831	0.56	1/20
SCHEMBL18935832	0.55	1/20
SCHEMBL18936509	0.55	1/20
SCHEMBL18935811	0.55	1/20
SCHEMBL18936394	0.54	1/20
SCHEMBL18936206	0.53	1/20
SCHEMBL18936217	0.53	1/20

Clinical trials — most relevant to DDHD2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Pharmacogenetics of Disulfiram for Cocaine	PHASE2	COMPLETED
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level	PHASE2	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations	EARLY_PHASE1	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Discovering the Gene(s) Causing Developmental Dysplasia of the Hip (DDH)	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Genetic Mechanisms and Additional Risk Factors Underlying Hip Dysplasia	nan	COMPLETED
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Genetics and Psychopathology in the 22q11 Deletion Syndrome	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal	nan	COMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome.	nan	COMPLETED
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration	nan	UNKNOWN
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)	nan	RECRUITING
Research for Genetic Factors Involved in Congenital Dislocation of Hip: Genome-wide Association Study in Grand West France	nan	COMPLETED
Microarray Analysis in Syndromic Obesity	nan	COMPLETED
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
Issues Surrounding Prenatal Genetic Testing for Achondroplasia	nan	COMPLETED
Phenotypic Exploration of Autism Spectrum Disorders Retrospective and Prospective Data	nan	RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
National Study on Autism Spectrum Disorder in China	nan	COMPLETED
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions	nan	RECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Evaluating Face-Recognition Technology in Syndrome Diagnosis	nan	COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study	nan	COMPLETED
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a DDHD2 binder may also engage these)

Protein	Name	Similarity
Q80Y98	—	1.000	Q80Y98 →
SEC23IP	SEC23-interacting protein	0.994	landscape →
G5EEM9	—	0.992	G5EEM9 →
Q6NZC7	—	0.992	Q6NZC7 →
Q8W5R2	—	0.991	Q8W5R2 →
Q5SNQ7	—	0.991	Q5SNQ7 →
Q7Z401	—	0.990	Q7Z401 →
P43125	—	0.990	P43125 →
Q5XHF8	—	0.990	Q5XHF8 →
P87109	—	0.990	P87109 →
NFKB1	Nuclear factor NF-kappa-B p105 subunit	0.990	landscape →
F4J8C6	—	0.989	F4J8C6 →
Q8BX57	—	0.989	Q8BX57 →
P25799	—	0.989	P25799 →
B4NBB0	—	0.988	B4NBB0 →
KDM5B	Lysine-specific demethylase 5B	0.988	landscape →
Q6ZQB6	—	0.988	Q6ZQB6 →
Q92503	—	0.988	Q92503 →
Q84WW3	—	0.988	Q84WW3 →
Q96JX3	—	0.988	Q96JX3 →
Q69ZS7	—	0.988	Q69ZS7 →
Q6NTN5	—	0.988	Q6NTN5 →
Q80U56	—	0.987	Q80U56 →
INPP5B	Type II inositol 1,4,5-trisphosphate 5-phosphatase	0.987	landscape →
Q9H1H9	—	0.987	Q9H1H9 →
Q3U213	—	0.987	Q3U213 →
Q8VIJ5	—	0.987	Q8VIJ5 →
Q3UMY5	—	0.987	Q3UMY5 →
Q2KHZ2	—	0.987	Q2KHZ2 →
B3P4N5	—	0.987	B3P4N5 →