Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 14/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.36 |
| ▸ | CDK4 | P11802 | 5/20 | 0.36 |
| ▸ | CCND1 | P24385 | 5/20 | 0.36 |
| ▸ | CDK7 | P50613 | 5/20 | 0.36 |
| ▸ | CCNH | P51946 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK14 | O94921 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870905 | 0.83 | PDE10A (0.51) | CDK2CCNA1CCNA2CHEK1CDK9 | |
| SCHEMBL26871132 | 0.78 | PDE10A (0.49) | CDK2CCNA1CCNA2CHEK1CDK9 | |
| SCHEMBL26871653 | 0.77 | CDK9 (0.58) | CDK2CCNA1CCNA2CDK9CCNT1 | |
| SCHEMBL26869183 | 0.75 | KDM4E (0.40) | CDK2CCNA1CCNA2CHEK1KDM4E | |
| SCHEMBL26871658 | 0.75 | CDK9 (0.65) | CDK2CCNA1CCNA2CDK9CCNT1 | |
| SCHEMBL26868395 | 0.73 | PIM1 (0.36) | CDK2CCNA1CCNA2CHEK1KDM4E | |
| SCHEMBL7846641 | 0.72 | CHEK1 (0.68) | CDK2CCNA1CCNA2CHEK1CDK9 | |
| SCHEMBL26868450 | 0.71 | CDK2 (0.35) | CDK2CCNA1CCNA2CHEK1KDM4E | |
| SCHEMBL4431791 | 0.70 | ALDH1A1 (0.50) | CDK2CCNA1CCNA2CHEK1KDM4E | |
| SCHEMBL7885210 | 0.69 | PDE10A (0.43) | CDK2CCNA1CCNA2CHEK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |