Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26885154 | 0.90 | LMNA (0.56) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL26885158 | 0.81 | KMT2A (0.47) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL26885062 | 0.79 | MTNR1A (0.50) | LMNAPOLBKMT2ACYP1A2NPC1 | |
| SCHEMBL4962039 | 0.79 | MEN1 (0.52) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL27553611 | 0.79 | PTPN1 (0.53) | LMNAPOLBKMT2AMEN1CYP3A4 | |
| SCHEMBL27395497 | 0.78 | ALOX15 (0.51) | LMNASMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL23909587 | 0.77 | ALDH1A1 (0.54) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL13761375 | 0.77 | LMNA (0.60) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL23909569 | 0.77 | ALDH1A1 (0.53) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL26885768 | 0.77 | MTNR1A (0.46) | LMNAPOLBKMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | ACE2, ACE, SARS1 | LMNA 2523/4885SMN1; SMN2 4878/4885POLB 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.