Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26887004 | 0.82 | GRM5 (0.42) | KDM4EALDH1A1MEN1NPC1HPGD | |
| SCHEMBL26686661 | 0.80 | GRM4 (0.47) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL26886938 | 0.73 | APP (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL26686308 | 0.73 | DHFR (0.47) | ALDH1A1CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL29428997 | 0.73 | ALDH1A1 (0.59) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL26886953 | 0.72 | ASIC3 (0.44) | ALDH1A1RETEGFRERBB2 | |
| SCHEMBL1922269 | 0.72 | CYP3A4 (0.76) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL25320861 | 0.70 | TLR7 (0.41) | NR4A2NOS3NOS2 | |
| SCHEMBL26686371 | 0.70 | NOS2 (0.33) | NOS3NOS2BACE1 | |
| SCHEMBL26686605 | 0.70 | AHCY (0.40) | ALDH1A1CYP3A4NR4A2NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |