Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689105 | 1.00 | ALOX15 (0.41) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL14099994 | 0.86 | ALOX5 (0.45) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL28241466 | 0.81 | GPR35 (0.38) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL6050795 | 0.77 | ALOX5 (0.42) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL2691198 | 0.76 | ALOX15 (0.38) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL2688868 | 0.76 | ALOX15 (0.38) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL19927819 | 0.73 | ALOX5 (0.41) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL16405011 | 0.73 | ALOX5 (0.41) | ALOX15CYP3A4MEN1TP53ALOX5 | |
| SCHEMBL12925772 | 0.71 | PTGS2 (0.42) | CYP3A4TP53PTGS2GPR35 | |
| SCHEMBL12279693 | 0.71 | ESR1 (0.42) | CYP3A4TP53PTGS2TNNC1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168671-B2 | Synthesis of thieno[3,4-b]thiophene, thieno[3,4-b]furan, related compounds and their derivatives and use thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | THE UNIVERSITY OF CONNECTICUT | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326187-A1 | SYNTHESIS OF THIENO[3,4-b]THIOPHENE, THIENO[3,4-b]FURAN, RELATED COMPOUNDS AND THEIR DERIVATIVES AND USE THEREOF | TENT4B, TERB1, CYP4B1 | ALOX15 1394/4885CYP3A4 30/4885MEN1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.