Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | HPGDS | O60760 | 2/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784584 | 0.84 | HPGDS (0.73) | IKBKBEPHX2HPGDS | |
| SCHEMBL6612574 | 0.84 | HPGDS (0.60) | IKBKBRAB9AMEN1POLBKMT2A | |
| SCHEMBL27623980 | 0.83 | RAB9A (0.71) | RAB9AMEN1POLBKMT2AHDAC1 | |
| SCHEMBL1761545 | 0.83 | RAB9A (0.92) | RAB9AMEN1POLBKMT2AHDAC1 | |
| SCHEMBL28541614 | 0.83 | EPHX2 (0.58) | IKBKBRAB9AMEN1POLBKMT2A | |
| SCHEMBL27565420 | 0.83 | ESRRG (0.59) | IKBKBHDAC6EPHX2HPGDSTP53 | |
| SCHEMBL27565581 | 0.83 | IKBKB (0.71) | IKBKBRAB9AMEN1POLBKMT2A | |
| SCHEMBL29922717 | 0.83 | EPHX2 (0.58) | IKBKBRAB9AMEN1POLBKMT2A | |
| SCHEMBL10275320 | 0.82 | RAB9A (0.69) | RAB9AMEN1POLBKMT2AHDAC1 | |
| SCHEMBL6378947 | 0.81 | IKBKB (1.00) | IKBKBRAB9AMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2023233024-A1 | DPP9 BINDING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2023-12-07 | — | — | WO | disclosed |
| EP-3274341-B1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA LECB | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2022-11-02 | — | — | EP | disclosed |
| CN-107531686-B | Inhibitors of pseudomonas aeruginosa LecB | 亥姆霍兹感染研究中心有限责任公司 | 2021-07-09 | — | — | CN | disclosed |
| US-10407398-B2 | Inhibitors of Pseudomonas aeruginosa LecB | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-09-10 | — | — | US | disclosed |
| US-20180155310-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA LECB | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2018-06-07 | — | — | US | disclosed |
| EP-3045457-B1 | SUBSTITUTED PYRIMIDINYLPYRROLOPYRIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2018-05-09 | — | — | EP | disclosed |
| EP-3274341-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA LECB | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2018-01-31 | — | — | EP | disclosed |
| CN-107531686-A | Pseudomonas aeruginosa LecB inhibitor | 亥姆霍兹感染研究中心有限责任公司 | 2018-01-02 | — | — | CN | disclosed |
| US-8546413-B2 | Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2013-10-01 | — | — | US | disclosed |
| US-20120178770-A1 | SUBSTITUTED PYRIMIDINYLPYRROLOPYRIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-07-12 | — | — | US | disclosed |
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| CN-102256969-A | Compounds that modulate intracellular calcium | CALCIMEDICA INC | 2011-11-23 | — | — | CN | disclosed |
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| EP-2009004-A1 | NOVEL PIPERAZINE COMPOUND, AND USE THEREOF AS HCV POLYMERASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2008-04-03 | — | — | US | disclosed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | disclosed |
| CN-100345847-C | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | disclosed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | HAVCR2, AADAC, DNPEP | IKBKB 173/4885RAB9A 4538/4885MEN1 4883/4885 |
| US-20180155310-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA LECB | FUCA1, ALG1, FUCA2 | IKBKB 735/4885RAB9A 1973/4885MEN1 4081/4885 |
| US-10407398-B2 | Inhibitors of Pseudomonas aeruginosa LecB | FUCA1, ALG1, FUCA2 | IKBKB 735/4885RAB9A 1973/4885MEN1 4081/4885 |
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | POLR1C, POLR2E, POLR2H | IKBKB 513/4885RAB9A 3868/4885MEN1 4872/4885 |
| US-20120178770-A1 | SUBSTITUTED PYRIMIDINYLPYRROLOPYRIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP3K1 | IKBKB 421/4885RAB9A 1307/4885MEN1 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.