Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497134 | 0.72 | GAA (0.45) | GAAKMT2AALDH1A1LMNAPDE1A | |
| SCHEMBL15041024 | 0.71 | BACE1 (0.32) | CRHR1PDE1APDE1BPDE1CGRIN2B | |
| SCHEMBL10572472 | 0.69 | KMT2A (0.50) | GAAKMT2AALDH1A1LMNABRD4 | |
| SCHEMBL981480 | 0.66 | KMT2A (0.54) | GAAKMT2AALDH1A1LMNAPDE1A | |
| SCHEMBL12826268 | 0.66 | GAA (0.40) | GAAKMT2AALDH1A1PDE1APDE1B | |
| SCHEMBL10366469 | 0.66 | GAA (0.50) | GAAKMT2AALDH1A1LMNABRD4 | |
| SCHEMBL21281700 | 0.65 | HTT (0.44) | GAAKMT2AALDH1A1LMNAPDE1A | |
| SCHEMBL12826267 | 0.65 | GAA (0.53) | GAAKMT2AALDH1A1LMNABRD4 | |
| SCHEMBL8281636 | 0.65 | ALDH1A1 (0.39) | KMT2AALDH1A1LMNABPTFMEN1 | |
| SCHEMBL23459964 | 0.62 | KMT2A (0.41) | KMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284801-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | Janssen Biotech, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |