Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 3/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | FES | P07332 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923984 | 0.82 | ALOX5AP (0.72) | BRD4CREBBPGRIA1CACNG8ALOX5AP | |
| SCHEMBL10710464 | 0.80 | GRIA1 (0.54) | BRD4CREBBPGRIA1CACNG8AHR | |
| SCHEMBL5782680 | 0.77 | GRIA1 (0.78) | BRD4CREBBPGRIA1CACNG8ALOX5AP | |
| SCHEMBL4408889 | 0.76 | TDP2 (0.65) | BRD4CREBBPGRIA1CACNG8AHR | |
| SCHEMBL4406924 | 0.74 | CHEK1 (0.58) | BRD4CREBBPGRIA1CACNG8AHR | |
| SCHEMBL8350056 | 0.72 | CA1 (0.54) | ALOX5APFEN1 | |
| SCHEMBL7214241 | 0.71 | CA12 (0.47) | ALOX5APFEN1TRPV1 | |
| SCHEMBL16321159 | 0.71 | GRIA1 (0.47) | BRD4CREBBPGRIA1CACNG8ALOX5AP | |
| SCHEMBL14362208 | 0.70 | PNMT (0.57) | — | |
| SCHEMBL23143517 | 0.70 | GSK3B (0.61) | BRD4CREBBPGRIA1CACNG8AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236920-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-12-14 | — | — | WO | disclosed |