Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659062 | 0.82 | MAPT (0.32) | MAPTKDM4ENSD2MAPK1LMNA | |
| SCHEMBL8749824 | 0.82 | MAPT (0.39) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL4450055 | 0.73 | SIRT1 (0.40) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL11822569 | 0.68 | MAPT (0.42) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL17292796 | 0.68 | MAPK1 (0.59) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL1549590 | 0.67 | MAPT (0.41) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL3790004 | 0.67 | MAPT (0.49) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL10388324 | 0.67 | TUBB4A (0.34) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| Hydrogen Sulfide SCHEMBL28060126 | 0.67 | MAPK1 (0.58) | MAPTKDM4ENSD2MAPK1TUBB4A | |
| SCHEMBL16581614 | 0.66 | MAPT (0.33) | MAPTKDM4ENSD2MAPK1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11181519-B2 | System and method for differential diagnosis of diseases | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-11-23 | — | — | US | disclosed |
| US-20190271685-A1 | SYSTEM AND METHOD FOR DIFFERENTIAL DIAGNOSIS OF DISEASES | TECHNION RESEARCH & DEVLOPMENT FOUNDATION LIMITED (IL) | 2019-09-05 | — | — | US | disclosed |
| US-9528979-B2 | Breath analysis of pulmonary nodules | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2016-12-27 | — | — | US | disclosed |
| US-8945935-B2 | Diagnosing, prognosing and monitoring multiple sclerosis | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2015-02-03 | — | — | US | disclosed |
| US-20130150261-A1 | BREATH ANALYSIS OF PULMONARY NODULES | TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD. (IL) | 2013-06-13 | — | — | US | disclosed |
| US-20130034910-A1 | DIAGNOSING, PROGNOSING AND MONITORING MULTIPLE SCLEROSIS | RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES (IL) | 2013-02-07 | — | — | US | disclosed |
| US-20120104362-A1 | Formation of ordered thin films of organics on metal oxide surfaces | NATIONAL SCIENCE FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-20050285101-A1 | Formation of ordered thin films of organics on metal oxide surfaces | NATIONAL SCIENCE FOUNDATION | 2005-12-29 | — | — | US | disclosed |
| WO-2005122293-A2 | FORMATION OF ORDERED THIN FILMS OF ORGANICS ON METAL OXIDE SURFACES | PRINCETON UNIVERSITY (US) | 2005-12-22 | — | — | WO | disclosed |