SCHEMBL8749824

SCHEMBL8749824

[c]1ccc(Sc2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
MAPK1 P28482 1/20 0.39
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33
TUBA1C Q9BQE3 1/20 0.33
TUBB6 Q9BUF5 1/20 0.33
TUBB2B Q9BVA1 1/20 0.33
TUBB1 Q9H4B7 1/20 0.33
SIRT1 Q96EB6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2693785 0.82 MAPT (0.39) MAPTKDM4ENSD2MAPK1TUBB4A
SCHEMBL7708325 0.71 ALDH1A1 (0.37) MAPTKDM4ETUBB4ATUBBTUBA3C
SCHEMBL7708543 0.71 ALDH1A1 (0.33)
SCHEMBL891578 0.71 LMNA (0.36) MAPTMAPK1LMNAHTT
SCHEMBL8112261 0.69 CYP2A6 (0.37) MAPTLMNAHTT
SCHEMBL15757626 0.69 LMNA (0.34) MAPTLMNAHTT
SCHEMBL7070227 0.69 BRD4 (0.36) MAPTKDM4EADORA2ALMNAHTT
SCHEMBL15757985 0.69 ALDH1A1 (0.37) MAPTKDM4EMAPK1LMNAHTT
SCHEMBL7708795 0.68 ALDH1A1 (0.30)
SCHEMBL17292796 0.68 MAPK1 (0.59) MAPTKDM4ENSD2MAPK1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764290-A1 PRINTING PROCESS ZENECA LIMITED (GB) 1997-03-26 EP disclosed
WO-1995034024-A1 PRINTING PROCESS ZENECA LIMITED (GB) 1995-12-14 WO disclosed
WO-1989003816-A1 DIVINYL EPOXY ETHERS GAF CORPORATION (US) 1989-05-05 WO disclosed