SCHEMBL6659062

SCHEMBL6659062

[c]1ccc(-c2ccccc2)c(-c2ccccc2)c1Sc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NSD2 O96028 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2693785 0.82 MAPT (0.39) MAPTKDM4ENSD2MAPK1LMNA
SCHEMBL17292796 0.72 MAPK1 (0.59) MAPTKDM4ENSD2MAPK1ALDH1A1
SCHEMBL891578 0.71 LMNA (0.36) MAPTMAPK1ALDH1A1LMNAHTT
Hydrogen Sulfide SCHEMBL28060126 0.70 MAPK1 (0.58) MAPTKDM4ENSD2MAPK1ALDH1A1
SCHEMBL6829533 0.69 CYP2A6 (0.36) MAPTALDH1A1LMNAHTT
SCHEMBL8497176 0.69 BACE1 (0.43) MAPTKDM4EMAPK1ALDH1A1LMNA
SCHEMBL522214 0.69 HSD17B10 (0.41) MAPTKDM4EMAPK1ALDH1A1TDP1
SCHEMBL999508 0.69 LMNA (0.34) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL6250246 0.69 LMNA (0.34) MAPTMAPK1ALDH1A1LMNAHTT
SCHEMBL8749824 0.68 MAPT (0.39) MAPTKDM4ENSD2MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242818-A1 Deodorizing agent for sulfur-or nitrogen-containing initiators UCB, S.A. (BE) 2004-12-02 US disclosed
EP-1438347-A1 DEODORIZING AGENT FOR SULFUR- OR NITROGEN-CONTAINING INITIATORS UCB, S.A. (BE) 2004-07-21 EP disclosed
US-20030152862-A1 Deodorizing agent for sulfur- or nitrogen-containing initiators UCB, S. A. (BE) 2003-08-14 US disclosed
US-20030108810-A1 Deodorizing agent for sulfur- or nitrogen-containing salt photoinitiators UCB, S.A. (BE) 2003-06-12 US disclosed
WO-2003018663-A1 DEODORIZING AGENT FOR SULFUR- OR NITROGEN-CONTAINING INITIATORS UCB, S.A. (BE) 2003-03-06 WO disclosed
EP-1214630-A2 MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2002-06-19 EP disclosed
WO-2001007506-A2 MICROFABRICATED DEVICES AND METHOD OF MANUFACTURING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2001-02-01 WO disclosed
US-4286047-A A RELEASEABLE ADHESIVE COMPRISING AN ADDITION POLYMER HAVING EPOXY GROUPS AND A PHOTOSENSITIVE CROSSLINKING PROMOTOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-08-25 US disclosed