SCHEMBL2694733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2770912	0.78	DCLRE1B (0.59)	SGK1CAMKK2NEK2GABRPGABRD
	SCHEMBL21857153	0.77	KMT2A (0.59)	CAMKK2ALPLKDM4EALDH1A1
	SCHEMBL16057551	0.74	SGK1 (0.46)	SGK1CAMKK2NEK2GABRPGABRD
	SCHEMBL1759307	0.74	KMO (0.53)	RAB9ASMN1; SMN2CA12CA9NPC1
	Hydrochloric Acid SCHEMBL1502412	0.73	KMO (0.51)	RAB9ASMN1; SMN2CA12CA9NPC1
	SCHEMBL10397478	0.72	DCLRE1B (0.72)	SGK1CAMKK2DCLRE1BDCLRE1AHSD17B1
	SCHEMBL1502364	0.72	KDM4E (0.46)	CAMKK2RAB9ASMN1; SMN2NPC1KDM4E
	Hydrochloric Acid SCHEMBL1502313	0.70	KDM4E (0.45)	CAMKK2RAB9ASMN1; SMN2NPC1KDM4E
	SCHEMBL4482880	0.70	METAP2 (0.49)	RAB9ASMN1; SMN2ALPLCA12CA9
	SCHEMBL21857189	0.69	KDM4E (0.50)	RAB9ASMN1; SMN2NPC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.