Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355308 | 0.83 | PRCP (0.50) | ALDH1A1KDM4EGAAPRCP | |
| SCHEMBL30804802 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EPRCP | |
| SCHEMBL29035907 | 0.80 | CA1 (0.38) | ALDH1A1MAPTKDM4EPRCP | |
| SCHEMBL28267065 | 0.79 | PNMT (0.37) | ALDH1A1MAPTPNMTKDM4EPRCP | |
| SCHEMBL6920787 | 0.79 | CA1 (0.40) | ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL29383585 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAPRCP | |
| SCHEMBL5708850 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAPRCP | |
| SCHEMBL4746005 | 0.76 | CYP2D6 (0.34) | ALDH1A1MAPTKDM4E | |
| SCHEMBL29644910 | 0.71 | HTR6 (0.42) | — | |
| SCHEMBL6468720 | 0.71 | PRCP (0.45) | ALDH1A1MAPTPNMTPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108631-A1 | Sulfonamides for the Modulation of PKM2 | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108631-A1 | Sulfonamides for the Modulation of PKM2 | PDK1, PDK4, PDK2 | ALDH1A1 2275/4885MAPT 3865/4885PNMT 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.