Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.35 |
| ▸ | NOS2 | P35228 | 6/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409265 | 0.79 | NOS3 (0.35) | NOS3NOS2NOS1GRM4UHRF1 | |
| SCHEMBL30068111 | 0.75 | P2RX3 (0.39) | — | |
| SCHEMBL26646817 | 0.75 | P2RX3 (0.39) | — | |
| SCHEMBL879562 | 0.70 | — | — | |
| SCHEMBL31656490 | 0.70 | — | — | |
| SCHEMBL1586143 | 0.70 | — | — | |
| SCHEMBL16510448 | 0.70 | LMNA (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL28432870 | 0.69 | LMNA (0.48) | NOS3NOS2NOS1UHRF1 | |
| Hydrochloric Acid SCHEMBL29151203 | 0.69 | NUDT1 (0.46) | NOS3NOS2NOS1GRM4NUDT1 | |
| SCHEMBL11888329 | 0.68 | PDE10A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858915-B2 | Polo like kinase 4 inhibitors | ORIC PHARMACEUTICALS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858915-B2 | Polo like kinase 4 inhibitors | PLK4, PLK2, PLK3 | NOS3 3618/4885NOS2 3963/4885NOS1 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.