SCHEMBL26975355

SCHEMBL26975355

CCN1CCN(S(=O)(=O)NC(=O)Nc2c(C(C)C)cccc2C(C)C)CC1

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26975354 0.87 NLRP3 (0.42) —
SCHEMBL26975465 0.86 MEN1 (0.48) MEN1KMT2ATDP1
SCHEMBL26975357 0.86 — —
SCHEMBL7572034 0.86 MEN1 (0.58) MEN1KMT2ATDP1
SCHEMBL7567422 0.85 MEN1 (0.56) MEN1KMT2ATDP1
SCHEMBL26975353 0.84 NLRP3 (0.51) —
SCHEMBL26975351 0.83 NLRP3 (0.52) —
SCHEMBL26975364 0.83 NLRP3 (0.52) —
SCHEMBL26975371 0.82 NLRP3 (0.51) —
SCHEMBL26975376 0.82 NLRP3 (0.51) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD MEN1 2219/4885KMT2A 3753/4885TDP1 2296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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