SCHEMBL26975364

SCHEMBL26975364

CC(C)c1cccc(C(C)C)c1NC(=O)NS(=O)(=O)N1CCOCC1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ NLRP3 Q96P20 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572034 0.88 MEN1 (0.58) NLRP3
SCHEMBL7567422 0.87 MEN1 (0.56) NLRP3
SCHEMBL26975363 0.86 ACHE (0.44) NLRP3
SCHEMBL31055722 0.85 ACHE (0.41) NLRP3
SCHEMBL31055693 0.85 NLRP3 (0.48) NLRP3
SCHEMBL26975351 0.85 NLRP3 (0.52) NLRP3
SCHEMBL26975353 0.84 NLRP3 (0.51) NLRP3
SCHEMBL26975371 0.84 NLRP3 (0.51) NLRP3
SCHEMBL26975376 0.84 NLRP3 (0.51) NLRP3
SCHEMBL26975355 0.83 MEN1 (0.52) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 — — EP claimed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 — — US disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD NLRP3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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