Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26977144 | 0.90 | JAK2 (0.38) | CDK2CDK1CDK7CDK9GAA | |
| SCHEMBL26977376 | 0.85 | MAPT (0.36) | EGFRMAPTLRRK2 | |
| SCHEMBL27241032 | 0.82 | CCNT1 (0.42) | CDK2CDK1CDK7CDK9CCNT1 | |
| SCHEMBL29928848 | 0.82 | CCNT1 (0.42) | CDK2CDK1CDK7CDK9CCNT1 | |
| SCHEMBL29929049 | 0.79 | VCAM1 (0.41) | GAAALDH1A1EGFRERBB2ELANE | |
| SCHEMBL26977398 | 0.79 | VCAM1 (0.41) | GAAALDH1A1EGFRERBB2ELANE | |
| SCHEMBL23611947 | 0.76 | CDK2 (0.38) | CDK2CDK1CDK7CDK9CCNT1 | |
| SCHEMBL26977200 | 0.74 | MKNK2 (0.38) | CDK2EGFRJAK2JAK1TYK2 | |
| SCHEMBL29929298 | 0.73 | CDK2 (0.41) | CDK2CDK1CDK7CDK9CCNT1 | |
| SCHEMBL29929752 | 0.73 | CCNT1 (0.41) | CDK2CDK9CCNT1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4297873-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | Tyra Biosciences, Inc. (US) | 2024-01-03 | — | — | EP | disclosed |