Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 2/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392150 | 0.82 | RAB9A (0.32) | ARKMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL30415860 | 0.81 | PTPN1 (0.36) | ALDH1A1 | |
| SCHEMBL21392152 | 0.81 | PTPN1 (0.36) | ALDH1A1 | |
| SCHEMBL28477374 | 0.79 | CASP6 (0.41) | ARKMT2AMEN1NR3C2RAB9A | |
| SCHEMBL21373801 | 0.74 | AAK1 (0.36) | — | |
| SCHEMBL26977288 | 0.70 | CTPS1 (0.64) | — | |
| SCHEMBL21392311 | 0.70 | CTPS1 (0.47) | ARKMT2AMEN1ALDH1A1 | |
| SCHEMBL21392320 | 0.67 | USP2 (0.35) | ARKMT2AMEN1NR3C2RAB9A | |
| SCHEMBL21384620 | 0.67 | PTPN1 (0.39) | ALDH1A1 | |
| SCHEMBL30725707 | 0.67 | PTPN1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768674-B1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S A S (FR) | 2024-01-03 | — | — | EP | disclosed |