Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 6/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126101 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HRH3FDPS | |
| SCHEMBL2127270 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP3A4HSP90AA1HSP90AB1 | |
| SCHEMBL2127630 | 0.83 | ALDH1A1 (0.36) | ALDH1A1CYP3A4TDP1GAA | |
| SCHEMBL1284598 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CYP3A4 | |
| SCHEMBL2429204 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP3A4FDPS | |
| SCHEMBL1282504 | 0.77 | L3MBTL1 (0.37) | ALDH1A1CYP3A4HRH3TDP1MEN1 | |
| SCHEMBL1282484 | 0.77 | L3MBTL1 (0.39) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL1282373 | 0.75 | FDPS (0.37) | ALDH1A1CYP3A4HRH3FDPS | |
| SCHEMBL2125479 | 0.74 | ACLY (0.37) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL1282179 | 0.74 | FDPS (0.36) | ALDH1A1HRH3FDPSLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | ALDH1A1 1943/4885CYP3A4 19/4885HRH3 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.