Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31686074 | 0.96 | GPR52 (0.41) | GPR52NUDT1MEN1MAPTKMT2A | |
| SCHEMBL26985070 | 0.86 | NUDT1 (0.40) | GPR52NUDT1MEN1MAPTKMT2A | |
| SCHEMBL26985124 | 0.82 | SYK (0.34) | NUDT1S1PR3TGFBR1 | |
| SCHEMBL26984842 | 0.81 | NUDT1 (0.38) | NUDT1MEN1MAPTKMT2AMKNK1 | |
| SCHEMBL26984982 | 0.81 | FPR2 (0.36) | KDR | |
| SCHEMBL30746582 | 0.80 | DHODH (0.38) | GPR52KDR | |
| SCHEMBL26985057 | 0.80 | DHODH (0.38) | GPR52KDR | |
| SCHEMBL26985281 | 0.79 | SSTR4 (0.35) | — | |
| SCHEMBL30746490 | 0.78 | NUDT1 (0.38) | GPR52NUDT1MEN1MAPTKMT2A | |
| SCHEMBL30746628 | 0.78 | NUDT1 (0.38) | GPR52NUDT1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |