SCHEMBL26986502

SCHEMBL26986502

O=c1cccc(CN2CCOCC2)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.53
CYP2A13 Q16696 7/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
KMT2A Q03164 1/20 0.46
NCF1 P14598 1/20 0.44
PARP1 P09874 1/20 0.44
HTT P42858 1/20 0.44
HRH3 Q9Y5N1 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TYMP P19971 1/20 0.42
TNKS O95271 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26986202 0.84 PABPC1 (0.54) CXCR4MEN1ALDH1A1KMT2AHRH3
SCHEMBL26986272 0.83 PABPC1 (0.57) MEN1ALDH1A1KMT2AHTTHRH3
SCHEMBL261373 0.75 HRH3 (0.42) CXCR4CYP2A13MEN1ALDH1A1KMT2A
SCHEMBL19458031 0.74 PABPC1 (0.72) CYP2A13ALDH1A1KMT2APARP1HRH3
SCHEMBL260734 0.74 DRD2 (0.63) CXCR4CYP2A13MEN1ALDH1A1KMT2A
SCHEMBL30602734 0.70 APAF1 (0.50) MEN1KMT2AHSD17B10
SCHEMBL29604383 0.69 CXCR4 (1.00) CXCR4CYP2A13MEN1ALDH1A1KMT2A
Bromide SCHEMBL29604076 0.68 CXCR4 (0.96) CXCR4CYP2A13MEN1ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL29604752 0.68 CXCR4 (0.96) CXCR4CYP2A13MEN1ALDH1A1KMT2A
SCHEMBL11196105 0.67 NCF1 (0.83) CXCR4CYP2A13MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551564-A2 ONE-STEP SYNTHESIS OF BETA-ALKYLIDENE-GAMMA-LACTONES The Scripps Research Institute (US) 2025-05-14 EP disclosed
WO-2024011131-A2 ONE-STEP SYNTHESIS OF BETA-ALKYLIDENE-GAMMA-LACTONES THE SCRIPPS RESEARCH INSTITUTE (US) 2024-01-11 WO disclosed
WO-2024011131-A2 ONE-STEP SYNTHESIS OF BETA-ALKYLIDENE-GAMMA-LACTONES THE SCRIPPS RESEARCH INSTITUTE (US) 2024-01-11 WO disclosed