Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27014767 | 0.82 | KMT2A (0.38) | ESR1ESR2SLC6A4SLC6A3KIF11 | |
| SCHEMBL27007239 | 0.79 | MAPK1 (0.31) | — | |
| SCHEMBL9667033 | 0.78 | ESR1 (0.46) | ESR1ESR2NR4A2SLC6A4SLC6A3 | |
| SCHEMBL27007179 | 0.78 | NR4A2 (0.34) | NR4A2MEN1KMT2AMMP2MMP12 | |
| SCHEMBL27007148 | 0.78 | NR4A2 (0.46) | NR4A2MEN1KMT2AMMP2MMP12 | |
| SCHEMBL27007170 | 0.75 | NR4A2 (0.36) | NR4A2MEN1KMT2AMMP2MMP12 | |
| SCHEMBL27007128 | 0.74 | EGLN1 (0.33) | LMNA | |
| SCHEMBL27007344 | 0.72 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27007187 | 0.71 | MAPK1 (0.31) | — | |
| SCHEMBL27007191 | 0.70 | EGLN1 (0.35) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091980-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2025-03-20 | — | — | US | disclosed |
| US-12110270-B2 | Systems and methods for generation of hyperpolarized materials | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-10-08 | — | — | US | disclosed |
| US-20240299593-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-09-12 | — | — | US | disclosed |
| CN-118103077-A | System and method for producing hyperpolarized material | 预视成像科技有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4359012-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technologies GmbH (DE) | 2024-05-01 | — | — | EP | disclosed |
| EP-4313174-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technologies GmbH (DE) | 2024-02-07 | — | — | EP | disclosed |
| CN-117529341-A | System and method for producing hyperpolarized material | 预视成像科技有限责任公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-01-18 | — | — | US | disclosed |
| WO-2022269350-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022200859-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technolgies GmbH (DE) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299593-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | ESR1 3050/4885ESR2 1706/4885NR4A2 4032/4885 |
| US-12110270-B2 | Systems and methods for generation of hyperpolarized materials | GLS2, HNMT, FH | ESR1 3050/4885ESR2 1706/4885NR4A2 4032/4885 |
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | ESR1 3050/4885ESR2 1706/4885NR4A2 4032/4885 |
| US-20250091980-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | ESR1 3050/4885ESR2 1706/4885NR4A2 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.