Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007158 | 0.82 | NPSR1 (0.38) | NPSR1ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL27007148 | 0.79 | NR4A2 (0.46) | NR4A2NPSR1ALDH1A1RAB9AKMT2A | |
| SCHEMBL27007181 | 0.75 | CHRNB2 (0.42) | NPSR1ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL27007162 | 0.75 | ESR1 (0.35) | NR4A2NPSR1ALDH1A1RAB9AKMT2A | |
| SCHEMBL27007179 | 0.74 | NR4A2 (0.34) | NR4A2ALDH1A1RAB9AKMT2AMMP2 | |
| SCHEMBL27007192 | 0.73 | — | — | |
| SCHEMBL27007344 | 0.73 | L3MBTL1 (0.40) | ALDH1A1KMT2ANPC1HTTL3MBTL1 | |
| SCHEMBL27007191 | 0.71 | EGLN1 (0.35) | LMNA | |
| SCHEMBL7396286 | 0.71 | NPSR1 (0.48) | NPSR1ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL7398659 | 0.70 | NPSR1 (0.47) | NPSR1ALDH1A1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091980-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2025-03-20 | — | — | US | disclosed |
| US-12110270-B2 | Systems and methods for generation of hyperpolarized materials | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-10-08 | — | — | US | disclosed |
| US-20240299593-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-09-12 | — | — | US | disclosed |
| CN-118103077-A | System and method for producing hyperpolarized material | 预视成像科技有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4313174-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technologies GmbH (DE) | 2024-02-07 | — | — | EP | disclosed |
| CN-117529341-A | System and method for producing hyperpolarized material | 预视成像科技有限责任公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-01-18 | — | — | US | disclosed |
| WO-2022200859-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technolgies GmbH (DE) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299593-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | NR4A2 4032/4885NPSR1 719/4885ALDH1A1 2576/4885 |
| US-12110270-B2 | Systems and methods for generation of hyperpolarized materials | GLS2, HNMT, FH | NR4A2 4032/4885NPSR1 719/4885ALDH1A1 2576/4885 |
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | NR4A2 4032/4885NPSR1 719/4885ALDH1A1 2576/4885 |
| US-20250091980-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | NR4A2 4032/4885NPSR1 719/4885ALDH1A1 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.