SCHEMBL27007239

SCHEMBL27007239

CC(C)OC(=O)C#CCOC(=O)C(=O)CCC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
SLC13A3 Q8WWT9 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27007128 0.83 EGLN1 (0.33) MAPK1SLC13A3EGLN1OR51E2
SCHEMBL27007162 0.79 ESR1 (0.35)
SCHEMBL27007124 0.79 TSHR (0.35)
SCHEMBL27007191 0.79 EGLN1 (0.35) MAPK1SLC13A3EGLN1OR51E2
SCHEMBL27007187 0.79 MAPK1 (0.31) MAPK1SLC13A3EGLN1OR51E2
SCHEMBL27007192 0.78
SCHEMBL29940800 0.75
SCHEMBL13019228 0.75 TSHR (0.43)
SCHEMBL10386154 0.74 CHRNB2 (0.38)
SCHEMBL29154670 0.74 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2025-03-20 US disclosed
US-12110270-B2 Systems and methods for generation of hyperpolarized materials NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-10-08 US disclosed
US-20240299593-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-09-12 US disclosed
CN-118103077-A System and method for producing hyperpolarized material 预视成像科技有限责任公司 2024-05-28 CN disclosed
EP-4359012-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2024-05-01 EP disclosed
EP-4313174-A1 SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2024-02-07 EP disclosed
CN-117529341-A System and method for producing hyperpolarized material 预视成像科技有限责任公司 2024-02-06 CN disclosed
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-01-18 US disclosed
WO-2022269350-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2022-12-29 WO disclosed
WO-2022200859-A1 SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technolgies GmbH (DE) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299593-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH MAPK1 3965/4885SLC13A3 85/4885EGLN1 422/4885
US-12110270-B2 Systems and methods for generation of hyperpolarized materials GLS2, HNMT, FH MAPK1 3965/4885SLC13A3 85/4885EGLN1 422/4885
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH MAPK1 3965/4885SLC13A3 85/4885EGLN1 422/4885
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH MAPK1 3965/4885SLC13A3 85/4885EGLN1 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.