SCHEMBL27007124

SCHEMBL27007124

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nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13019228 0.85 TSHR (0.43) TSHR
SCHEMBL29154670 0.80 TSHR (0.32) TSHR
SCHEMBL10386154 0.80 CHRNB2 (0.38) TSHR
SCHEMBL27014758 0.79
SCHEMBL27007239 0.79 MAPK1 (0.31)
SCHEMBL27014767 0.77 KMT2A (0.38)
SCHEMBL27007118 0.77 GLO1 (0.30)
SCHEMBL27014760 0.75 CTSK (0.33)
SCHEMBL29940811 0.75 CTSK (0.33)
SCHEMBL29154673 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2025-03-20 US disclosed
US-12110270-B2 Systems and methods for generation of hyperpolarized materials NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-10-08 US disclosed
CN-118103077-A System and method for producing hyperpolarized material 预视成像科技有限责任公司 2024-05-28 CN disclosed
EP-4359012-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2024-05-01 EP disclosed
EP-4313174-A1 SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2024-02-07 EP disclosed
CN-117529341-A System and method for producing hyperpolarized material 预视成像科技有限责任公司 2024-02-06 CN disclosed
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-01-18 US disclosed
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-01-18 US disclosed
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2024-01-18 US disclosed
WO-2022269350-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2022-12-29 WO disclosed
WO-2022200859-A1 SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technolgies GmbH (DE) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12110270-B2 Systems and methods for generation of hyperpolarized materials GLS2, HNMT, FH TSHR 3363/4885
US-20240018087-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH TSHR 3363/4885
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH TSHR 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.