SCHEMBL27008293

SCHEMBL27008293

COC(=O)c1[nH]c2cc(OCc3ccccc3)ccc2c1C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 2/20 0.54
CTSL P07711 2/20 0.54
ALDH1A1 P00352 5/20 0.51
HSD17B10 Q99714 4/20 0.51
USP2 O75604 2/20 0.51
TSHR P16473 1/20 0.51
HPGD P15428 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAOA P21397 1/20 0.49
MDH2 P40926 1/20 0.49
KDM4E B2RXH2 5/20 0.49
MAPT P10636 4/20 0.49
GAA P10253 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
ALOX15 P16050 1/20 0.49
FLT3 P36888 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
SRD5A2 P31213 1/20 0.47
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27142999 0.94 CTSV (0.53) CTSVCTSLALDH1A1HSD17B10USP2
SCHEMBL31498185 0.88 NR4A2 (0.58) CTSVCTSLALDH1A1HSD17B10USP2
SCHEMBL30710231 0.83 TUBB4A (0.49) CTSVCTSLALDH1A1HSD17B10USP2
SCHEMBL27027505 0.81 GPR17 (0.53) ALDH1A1HSD17B10USP2HPGDMAOA
SCHEMBL6824331 0.78 MAOB (0.56) CTSVCTSLALDH1A1HSD17B10HPGD
SCHEMBL2433763 0.77 MDH2 (0.69) ALDH1A1HPGDSMN1; SMN2MDH2NPC1
SCHEMBL19127960 0.76 KDM4E (0.58) CTSVCTSLALDH1A1HPGDSMN1; SMN2
Potassium Ion SCHEMBL31498179 0.76 CTSV (0.54) CTSVCTSLALDH1A1HSD17B10HPGD
SCHEMBL8406972 0.76 FLT3 (0.70) CTSVCTSLALDH1A1HSD17B10HPGD
SCHEMBL7256169 0.75 CTSV (0.66) CTSVCTSLALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547668-A1 BIFUNCTIONAL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE BIFUNCTIONAL COMPOUND, AND METHOD FOR TREATING ANDROGEN RECEPTOR RELATED DISEASE BY USING THE SAME Anhorn Medicines Co., Ltd. (TW) 2025-05-07 EP disclosed
US-20240336620-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE ANHORN MEDICINES CO., LTD. (TW) 2024-10-10 US disclosed
US-20240018149-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE ANHORN MEDICINES CO., LTD. (TW) 2024-01-18 US disclosed
US-20240018149-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE ANHORN MEDICINES CO., LTD. (TW) 2024-01-18 US disclosed
WO-2024002205-A1 BIFUNCTIONAL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE BIFUNCTIONAL COMPOUND, AND METHOD FOR TREATING ANDROGEN RECEPTOR RELATED DISEASE BY USING THE SAME ANHORN MEDICINES CO., LTD. (CN) 2024-01-04 WO disclosed
WO-2024002289-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE ANHORN MEDICINES CO., LTD. (CN) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336620-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE CRBN, UBQLN2, CBL CTSV 998/4885CTSL 2036/4885ALDH1A1 3876/4885
US-20240018149-A1 PROTEIN DEGRADATION COMPOUNDS AND METHODS OF USE MDM2, PSMG3, ADRM1 CTSV 387/4885CTSL 1252/4885ALDH1A1 4137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.