Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662567 | 0.85 | ROCK2 (0.46) | POLBL3MBTL1DPP4DPP8NPC1 | |
| SCHEMBL10272737 | 0.85 | ROCK2 (0.46) | POLBL3MBTL1DPP4DPP8NPC1 | |
| SCHEMBL13077437 | 0.84 | MEN1 (0.46) | POLBCYP2D6NPC1RAB9AHPGD | |
| SCHEMBL24135569 | 0.81 | NPC1 (0.42) | CYP2D6NPC1RAB9AHPGDMEN1 | |
| SCHEMBL23569770 | 0.81 | L3MBTL1 (0.39) | POLBL3MBTL1DPP4CYP2D6DPP8 | |
| SCHEMBL14259818 | 0.80 | ALDH1A1 (0.49) | POLBL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL20756191 | 0.80 | MVD (0.41) | POLBL3MBTL1ALDH1A1HCRTR2NPC1 | |
| SCHEMBL14569490 | 0.79 | HCRTR2 (0.44) | HCRTR2 | |
| SCHEMBL10272735 | 0.79 | POLB (0.66) | POLBL3MBTL1DPP4DPP8ALDH1A1 | |
| SCHEMBL12156743 | 0.79 | POLB (0.66) | POLBL3MBTL1DPP4DPP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | TORAY INDUSTRIES, INC. (JP) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | NSUN2, POLRMT, POLN | POLB 6/4885L3MBTL1 1465/4885DPP4 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.